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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A study compared treatment with cinacalcet versus treatment with placebo in subjects with known hyperparathyroidism. The primary outcome of the study was the proportion of study subjects with a mean intact parathyroid hormone level < 250 pg/mL. Among the cinacalcet group (n = 371), 43% of subjects achieved the primary outcome; among the placebo group (n =
370), 5% achieved the primary outcome (p<0.05).
Which of the following is the number needed to treat (NNT)?

A) 1
B) 3
C) 8
D) 14

2. Which of the following sources is most likely to publish the current recommendations from the Centers for Disease Control and Prevention regarding the use of recombinant hepatitis B Vaccine?

A) Clinical Infectious Diseases
B) Morbidity and Mortality Weekly Report
C) Journal of Hepatology
D) Medical Letter on Drugs and Therapeutics

3. Which of the following is an example of a sentinel event, as defined by the Joint Commission?

A) Death due to heart failure following discharge against medical advice
B) Removal of the Wrong breast during surgery
C) Death due to overdose of methylphenidate obtained from a brother's prescription
D) Administration of digoxin to the Wrong patient without adverse events

4. A 70-year-old man has completed a 14-day course of sulfamethoxazole/trimethoprim for Escherichia coli cystourethritis. The patient has a Foley catheter. A urine culture obtained 24 hours after the last antibiotic dose shows Candida albicans > 10x3 cfu/mL, RBC > 100 cells/hpf, and WBC = 10-20 cells/hpf. The patient is asymptomatic. What is the most appropriate management?

A) No anti-infective needed
B) Fluconazole orally daily for 5-10 days
C) Amphotericin bladder irrigation for 5-10 days
D) Posaconazole orally daily for 5-10 days

5. A 25-year-old man who weighs 80 kg is brought to the emergency department following a motor vehicle collision. He has severe facial contusions and a presumed closed head injury. His Glasgow Coma Scale score is 8. An emergency CT scan shows no evidence of intracranial bleeding. What should recommendations for therapy include?

A) Phenytoin 1,200 mg intravenously over 45 minutes, then an appropriate maintenance dose for one week
B) Fosphenytoin 25 PE/kg intravenous push, then an appropriate maintenance dose for one week
C) Diazepam 5 mg intravenously over 5 minutes, qh6 for one week
D) Dexamethasone 10 mg intravenously q6h for one week

Solutions: