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SASInstitute A00-282 Exam Syllabus Topics:
| Section | Weight | Objectives |
|---|---|---|
| Topic 1: Clinical Trials Data Structures | 10% | - Clinical domain structures - CDISC standards: SDTM, ADaM - Define.xml and dataset specifications |
| Topic 2: Apply Statistical Procedures for Clinical Trials | 15% | - Basic statistical analysis for clinical data - PROC MEANS, FREQ, TABULATE |
| Topic 3: Report Clinical Trials Results | 10% | - PROC REPORT and PROC PRINT - Produce tables, listings, and figures |
| Topic 4: Transform or Summarize Clinical Trials Data | 15% | - Data step manipulation - Aggregation and transposition - Derive variables and study days |
| Topic 5: Macro Programming for Clinical Trials | 15% | - Macro variables and parameters - Debugging macros - Create and call macros |
| Topic 6: Validate Clinical Trial Data Reporting | 20% | - Programming validation techniques - Validation principles - Use PROC COMPARE and log review |
| Topic 7: Manage Clinical Trials Data | 5% | - Access and explore clinical datasets - Use SQL and dictionary tables - Clean, merge, and subset data |
| Topic 8: Regulatory Submissions | 5% | - ICH and FDA guidelines - Compliance for clinical data reporting |
| Topic 9: Clinical Trials Process | 5% | - Derive programming requirements from protocol and CRF - Clinical trial lifecycle and protocol |
SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:
1. This question will ask you to provide lines of missing code.
Which ODS statements, inserted respectively in the two locations indicated above, create a report stored in a PDF file?
A) ods pdf open='AE.pdf';
ods pdf close;
B) ods file pdf='AE.pdf';
ods file close;
C) ods pdf file='AE.pdf';
ods pdf close;
D) ods file open='AE.pdf' type=pdf;
ods file close;
2. The following SAS program is submitted:
proc sort data=SASUSER.VISIT out=PSORT; by code descending date cost; run; Which statement is true regarding the submitted program?
A) The descending option applies to the variable CODE.
B) The descending option applies to the DATE and COST variables.
C) The variable CODE is sorted by ascending order.
D) The PSORT data set is stored in the SASUSER library.
3. Which of these tasks is NOT required for a validating programmer to state that an output has been independently validated using double programming once a PROC COMPARE has been run and shows the output electronically validates?
A) The output is using the correct title specified in the Statistical Analysis Plan.
B) Counts displayed in the columns are coherent.
C) The Statistical Analysis Plan has been approved and signed off by the sponsor.
D) The output is correctly paginated.
4. How does the code shown below help to validate report output?
data check;
set datlib.medhist;
mh_len = length(trim(mhcom1));
run;
proc freq data=check;
tables mh_len;
run;
A) It shows all the values for mhcom1 in the results.
B) It helps the programmer determine which observation has the longest value for mhcom1.
C) It writes all values of the mhcom1 variable that are longer than 200 in the results.
D) It shows all the values for the length of mhcom1 in the results.
5. The following question will ask you to provide a line of missing code. The following program is submitted to output observations from data set ONE that have more than one record per patient.
Please enter the line of code that will correctly complete the program. Note: Case is ignored. Do not add leading or trailing spaces to your answer.
A) id;
PTON run;
B) BYSUBJID;
BYSUBJID;
C) BYSUBJID;
D) BYSUBJID;
run;
Solutions:
| Question # 1 Answer: C | Question # 2 Answer: C | Question # 3 Answer: C | Question # 4 Answer: D | Question # 5 Answer: C |

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