USMLE United States Medical Licensing Examination : USMLE

Exam Code: USMLE

Exam Name: United States Medical Licensing Examination

Updated: Jul 23, 2026

Q & A: 400 Questions and Answers

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About USMLE United States Medical Licensing Examination : USMLE Exam

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USMLE United States Medical Licensing Examination

USMLE stands for United States Medical Licensing Examination. This is a series of medical exams coming in a few stages that all new doctors need to pass (starting from their time in med school) to be able to practice medicine.

USMLE Step 2 is a one-day (8 hours) exam. Similar to the Step 1, the test items are divided into blocks, and test item formats vary within each block, with the total number of exam questions equaling to 355.

Step 1 of the USMLE (United States Medical Licensing Examination) is the first part of the United States Medical Licensing Examination. It is open to medical school student and graduates to assess their ability to apply important concepts fundamental to the practice of medicine. While American medical students usually take USMLE Step 1 at the end of the second year of medical school, all graduates of foreign medical schools must take this exam is they intend to practice medicine in the United States.

USMLE Step 3 is open to candidates who already hold their USMLE Step 1 and Step 2 certificates. Step 3 is a two-day exam that assesses whether candidates are able apply medical knowledge and understanding of biomedical and clinical science essential to unsupervised medical practice. This is the final USMLE exam which leads to the license to practice medicine without supervision - the ultimate goal of medical students and professionals willing to practice medicine in the United States. Step 3 represents the final assessment of physicians assuming independent responsibility for delivering general medical care.

Reference: http://www.usmle.org/step-1/#question-formats

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USMLE USMLE Exam Syllabus Topics:

SectionObjectives
Topic 1: Human Development- Growth and Development
  • 1. Embryology
  • 2. Developmental Abnormalities
Topic 2: Gastrointestinal System- Digestive System Disorders
  • 1. Gastrointestinal Pathology
  • 2. Liver Disease
Topic 3: Reproductive System- Male and Female Reproductive Health
  • 1. Reproductive Physiology
  • 2. Reproductive Disorders
Topic 4: Musculoskeletal System- Bones, Joints, and Muscles
  • 1. Orthopedic Disorders
  • 2. Rheumatologic Diseases
Topic 5: Renal and Urinary System- Kidney and Urinary Disorders
  • 1. Renal Pathology
  • 2. Renal Physiology
Topic 6: Hematopoietic and Lymphoreticular Systems- Blood and Immune Disorders
  • 1. Anemias
  • 2. Leukemias and Lymphomas
  • 3. Coagulation Disorders
Topic 7: Multisystem Processes and Disorders- Systemic Conditions
  • 1. Infectious Diseases
  • 2. Nutrition
  • 3. Neoplasia
Topic 8: Endocrine System- Hormonal Regulation and Disease
  • 1. Adrenal Disorders
  • 2. Pituitary Disorders
  • 3. Thyroid Disorders
Topic 9: General Principles- Foundational Medical Sciences
  • 1. Physiology
  • 2. Microbiology
  • 3. Immunology
  • 4. Biochemistry
  • 5. Behavioral Sciences
  • 6. Pharmacology
  • 7. Genetics
  • 8. Pathology
Topic 10: Cardiovascular System- Cardiac and Vascular Disorders
  • 1. Heart Disease
  • 2. Vascular Pathology
Topic 11: Respiratory System- Pulmonary Medicine
  • 1. Lung Diseases
  • 2. Airway Disorders
Topic 12: Skin and Related Connective Tissue- Dermatologic Conditions
  • 1. Skin Neoplasms
  • 2. Inflammatory Skin Disorders
Topic 13: Central and Peripheral Nervous Systems- Neurologic Disorders
  • 1. Neurologic Diseases
  • 2. Neuropathology
  • 3. Neuroanatomy

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